Ewa Deelman led the development of Pegasus, a powerful scientific workflow management software that played a crucial role in the Nobel Prize-winning discovery of gravitational waves, confirming Einstein's General Theory of Relativity.

As a research professor at ISI, Deelman's work with Pegasus has automated complex computational tasks, enabling groundbreaking research across various fields. Pegasus has been used in numerous scientific domains, including astronomy, bioinformatics, earthquake science, gravitational wave physics, ocean science, and limnology. Her efforts have not only advanced scientific understanding but also showcased the transformative potential of computational tools in addressing some of the world's most significant challenges.